منابع مشابه
Unexpected toxicity in patients treated with iphosphamide.
A derivative of cyclophosphamide, 2,3-(TV, TV1-bis(2chloroethyl)diamido-l, 3, 2-oxazaphosphoridinoxyd (Iphosphamide), was less toxic in experimental systems than cyclophosphamide, while it had a broader antitumor spectrum. We studied this agent in a clinical trial of 37 patients with histologically proved, far-advanced malignant disease. The study was designed mainly to determine toxicity and d...
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INTRODUCTION Appendicular diverticula and associated diverticulitis is a rare disease. Patients present commonly with symptoms of acute appendicitis and require laparoscopic or open surgery. Diagnosis is usually made only on histology. Here, we present a rare case of acute diverticulitis of the appendix. CASE PRESENTATION A 33-year old gentleman presented with right iliac fossa pain of 3 days...
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Background: Cadmium is one of the most toxic heavy metals in our environment having a very strong ability to accumulate in body organs, especially in kidney. The present study was done to determine the genotoxicity and cytotoxicity in kidneys of rats exposed to cadmium. Methods: Male rats (n=30), kept in standard conditions were used in this study. The animals were randomly divided into 2 group...
متن کاملToxicity Evaluation of Essential oil of Trachyspermum ammi in Acute and Sub-chronic Toxicity Experiments
Background: Trachyspermum ammi is one of the prominent plant in traditional medicine of the east with several medicinal effects such as improvement of stomach disease, digestive disorder, diarrhea, hemorrhoid, bladder stones, respiratory disease and etc. Medicinal plants is one of the important reason of toxicity particularly in children and the elderly therefore, evaluation of the toxic effect...
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Objective: The plantCassia fistula L. (Caesalpiniaceae) is traditionally used to treat heart diseases, abdominal pain and fever. The present study was aimed to investigate the toxic effects acute and sub-acute administration of ethanol extract of C. fistula fruit (CFE) in male Wistar rats. Materials and Methods: In acute toxicity, the effects of a single oral dose (1000, 3000 and 5000 mg/kg) of...
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ژورنال
عنوان ژورنال: Nature
سال: 1964
ISSN: 0028-0836,1476-4687
DOI: 10.1038/201512a0